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Retatrutide, an innovative agent undergoing Phase III trials for obesity, T2DM, and non-alcoholic fatty liver disease, has demonstrated encouraging outcomes

Do not increase or skip doses without guidance

Appetite suppression, glucose regulation, and digestive slowing typically become stronger as dose intensity rises

Keshelava N, Frgala T, Krejsa J, Kalous O, Reynolds CP

Over a third also showed improvement in liver scarring of at least one stage Fat loss over muscle loss analysis from the STEP 1 trial found that the majority of weight lost on Wegovy was fat rather than muscle

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