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The realistic timeline: pivotal trial results by mid-2026, NDA submission by late 2026, FDA decision by mid to late 2027, and pharmacy availability by late 2027 or early 2028

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The mice were sacrificed, and livers were collected and quickly washed twice in ice-cold phosphate buffered saline (PBS)

Children should start at ~1/4 of adult (2 pumps per day) dosage and work up

Morton JI, McDonald SP, Salim A, Liew D, Shaw JE, Magliano DJ (2021) Projecting the incidence of type 2 diabetes-related end-stage kidney disease until 2040: a comparison between the effects of diabetes prevention and the effects of diabetes treatment