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Foods that are high sulfur may increase glutathione production
The FLAD1 gene is located on chromosome 1q21.3 and is composed of 7 exons that generate four alternatively spliced mRNAs each of which encode distinct isoforms of the enzyme
One possibility is that diminishing the cytosolic level of GSH suppresses its import into the ER, thereby elevating the ER GSSG/GSH ratio as well
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The third term is the loss of cysteine in the reaction catalyzed by GCS that makes glutamyl-cysteine and the fourth term represents the loss of cysteine to other pathways (for example to sulfate and taurine)
Yadav, P
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