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[3-5] What Nutrition21 discovered was that you could inhibit this process by blending the arginine with silica and inositol, which buffer it in the stomach and spare it from being degraded by enzymes

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Reinehr T, Kleber M, Toschke AM, Woelfle J, Roth CL

You can either move the day forward (taking it earlier) or backward (taking it later), then simply continue on that new day every week

This process, known as Phase I and Phase II detoxification, creates a significant amount of "oxidative stress." Think of this stress like the exhaust coming from a car engine