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Gustin JP, Karakas B, Weiss MB, Abukhdeir AM, Lauring J, Garay JP, Cosgrove D, Tamaki A, Konishi H, Konishi Y, Mohseni M, Wang G, Rosen DM, Denmeade SR, Higgins MJ, Vitolo MI, Bachman KE, Park BH (2009) Knockin of mutant PIK3CA activates multiple oncogenic pathways
While these results were statistically significant, they represent modest weight loss, particularly when compared to appetite-suppressing medications that typically produce more dramatic short-term results
The peptide also stimulates superoxide dismutase production, providing antioxidant protection against free radical damage
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Guo, S., & DiPietro, L
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