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10.1371/journal.pbio.1000052 PLoS Biol
doi: 10.1186/s13098-025-02045-4 175 KongXZhaoYWangXYuYMengYYanGet al
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For example, during acute or incipient tissue injury, senescent cells attract, anchor, and activate immune cells via the secretion of specific SASP factors and immunomodulators, facilitating transient immune activation that reinforces tissue plasticity and regeneration, thereby facilitating wound healing and tissue repair (22)
a separate 2009 study (Sackmann-Sala et al., Growth Hormone & IGF Research) confirmed GH/IGF-1 axis activation at 60-90 mcg/kg
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