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Fatty acid fragments such as pimelic and especially azelaic acids (C 7 and C 9 dicarboxylic acids, respectively) are generated from hydroperoxy fatty acids of the 9-LOX pathway with aldehydes, and these may be involved in systemic acquired resistance and the defence against pathogens
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DSIP may also stimulate the endogenous antioxidant system, influencing various enzymatic levels
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Hoyes KP, Morris ID, Hendry JH, Sharma HL
Underlying mechanisms of apoptosis in HepG2 cells induced by polyphyllin I through Fas death and mitochondrial pathways
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