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Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma

According to the company's blog content, users should expect a gradual titration process that involves starting at lower doses and increasing over weeks or months

Fasting glucose and insulin: Check every 2 weeks for the first 8 weeks, then monthly

At present, a large-scale phase III RCT of 2-year exenatide treatment in patients with PD, defined as a Hoen and Yahr (H&Y) stage of 2.5, is ongoing

However, our results do not necessarily suggest that everyone with type 2 diabetes should receive an SGLT2i, nor do they address other considerations about widespread SGLT2i use

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