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The 0.25 mg dose reaches lower peak concentrations but follows the same five to six week elimination timeline as higher maintenance doses
But the body wants balance
This was accompanied by a lack of reciprocal increase in fasting insulin secretion, implying impairment of fasting cell responsivity (as borne out by a decrease in b )
Some patients may still be better suited to an injectable treatment
If fatigue is severe or persistent, its important to discuss it with a healthcare professional to rule out other causes
Li S, Wu Y, Zhang J, Sun H, Wang X
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