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GLP-1s, first approved for type 2 diabetes in 2005, lower blood glucose, help avoid fatty liver disease, and help with obesity-related problems such as knee pain, sleep apnea, and gastroesophageal reflux
Christensen S, et al
Agmatine can inhibit the overactivation of IDO, increase 5-HT levels, and reduce the abnormally elevated glutamate/GABA ratio, ultimately exerting anti-epileptic effects while also improving depressive and cognitive symptoms [130]
These should be administered within 60 minutes before morning and evening meals (or the two main meals of the day, at least 6 hours apart) and should not be taken after meals
If IGF-1, glucose, or other markers move outside of expected ranges, scale back or stop dosing
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