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SCARs are strongly correlated with the HLA B*5801 allele and include drug rash accompanied by eosinophilia and systemic symptoms, StevensJohnson syndrome, and toxic epidermal necrosis

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It plays multiple roles in glucose homeostasis and appetite regulation

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For instance, the HARMONY 7 trial on liraglutide found that women achieved a 0.4% greater reduction in HbA1c levels compared to men