NS3 protein of HCV activates NADPH oxidase in Kupffer cells to increase production of ROS, which can exert oxidative stress on nearby cells (Thoren et al., 2004)
L-carnitine is a naturally occurring compound that can assist some challenges associated with autism
The entry is formulated and presented for analytical workflows, method development, and reproducibility studies in accredited research environments
2025: Novo Nordisk announced positive Phase 3 ESSENCE trial results for semaglutide in early Alzheimer's disease, reporting statistically significant slowing of cognitive and functional decline a breakthrough data package that could establish GLP-1 therapy as a neuroprotective agent and open an addressable market of 6.5 million Alzheimer's patients in the U.S
10.1016/j.cell.2005.07.002 Cell 140 PengY.HuentelmanM.SmithC.QiuS
The novel GLP-1RA geniposide was found to up-regulate the expression of -cell lymphoma 2 (Bcl-2), whereas reduce the activity of caspase 3, thereby protecting dopaminergic neurons in a MPTP mouse model of PD (66)