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The psychosocial aspects of fastingrooted in discipline, routine, and delayed gratificationmay contribute to better long-term glycaemic control and reduced emotional eating, which is commonly observed in patients with type 2 diabetes (100)

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Moreover, obese individuals demonstrate a decreased level of sarco/endoplasmic reticulum Ca 2+ -ATPase 2 (SERCA2) activity, which pumps the cytosolic Ca 2+ into the ER lumen [51]