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Important role of FTO in the survival of rare panresistant triple-negative inflammatory breast cancer cells facing a severe metabolic challenge

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Plant Cell 24(6):22792303

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pylori infection Intestinal permeability Inflammatory bowel disorders The gut and skin communicate through inflammatory and immune pathways often referred to as the gut-skin axis. When gut integrity becomes disrupted: Inflammatory cytokines increase Histamine signaling rises Immune activation escalates Skin barrier function worsens This inflammatory cascade may directly contribute to rosacea flares

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First, phase II clinical trials evaluating MOTS-c in type 2 diabetes and sarcopenia are in development, and their results will provide the first randomized controlled evidence in humans to define therapeutic doses with statistical rigor

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Nature 583 , 459468 (2020)

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