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The study authors note that side effects were very similar between the medications, and they found no significant differences in the rates of any adverse event People lost more weight on the medications if they didn't have diabetes, but even if they did, those taking Mounjaro lost a greater percentage of their starting weight than those taking Ozempic
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A study published in The New England Journal of Medicine in February 2021 focusing on the use of semaglutide (sold as Ozempic, Wegovy, and Rybelsus) for weight loss showed that people lost an average of 6.9 kg (or about 15.2 pounds) of body weight at the end of 40 weeks
The trial included almost 10,000 people with type 2 diabetes who had cardiovascular disease or chronic kidney disease
Tirzepatide is a dual-agonist targeting GLP-1 and GIP receptors, while retatrutide is a triple-agonist that also activates the glucagon receptor
