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If this happens to be the direct result of a deficit in localized methylation in scalp tissues, then vitamin B12 might help improve methylation and thereby improve Wnt / -catenin signaling, which would allow for hairs to grow longer, shed less prematurely, and (hopefully) not miniaturize as quickly

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These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2

Hyperpigmentation concerns