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They are not associated with cardiovascular protection beyond glucose lowering, so they are typically chosen when GLP-1 agonists or SGLT2 inhibitors are unsuitable
Incretin-mimetic drugs for obesity, such as semaglutide and tirzepatide, may lead to significant muscle mass loss
shown are the GLP-1-bound (orange) and TT-OAD2 bound (blue) GLP-1R
Tzortzis Nomikos, Harokopio University, Greece
More fat gets burned
Gum arabic is soluble in water
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