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Doses of folic acid greater than 0.1 mg per day may result in hematologic remission in patients with vitamin B 12deficiency

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doi:10.1016/j.bbrc.2010.05.108 Angelini G, Gardella S, Ardy M, Ciriolo MR, Filomeni G, Di Trapani G, Clarke F, Sitia R, Rubartelli A (2002) Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation

Bought 1.1 extra percentage points over 2.4 mg for 88% more drug, and was dropped before phase 3

Peptides can have functions that are a little bit like hormones, but theyre not quite hormones

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