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Clemmons, et al

The low expression of HOXA9 is associated with epithelial-mesenchymal transition (EMT), which may be a feature of tumor invasion in NSCLC patients

Since many Cys-GSTs characterized so far either structurally or biochemically have been shown to form mixed disulfides with GSH, there is little doubt that the catalytic cysteine performs a nucleophilic attack on GSH-conjugated substrates

Nausea is usually worse at the beginning and often diminishes after a few weeks of dose stabilization

Consistent with its more IGF1R-like behavior, we find that the L973F mutation in IR leads to decreased receptor internalization following insulin stimulation compared with WT-IR