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For Wegovy, this should occur within a specialist weight management service as specified by NICE guidance

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34 Another clue to the diagnosis is that patients with Wilson disease tend to develop Coombs-negative hemolytic anemia, which leads to a disproportionate elevation in aminotransferase levels, with aspartate aminotransferase being higher than alanine aminotransferase

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Rapid weight loss can increase physical activity, placing underlying stress on joints and connective tissue