These appear to implicate hitherto unrecognized metabolic mechanisms induced by fasting: antioxidative defense (ergothioneine, OA, carnosine), enhanced mitochondrial activity (organic acids in the TCA cycle), increased purine and pyrimidine anabolism, pentose phosphate pathway (sedoheptulose-7-phosphatase, pentose phosphate), and remodeling of signaling (hydroxybutyrate)
MK: Investigation, Writing original draft
doi: 10.1038/s41392-023-01570-w 170 DuanXHuTTuyghunELiZJingJXuDet al
Yoshinori Abe advises, "GLP-1 users should track body composition, waist size, strength, and metabolic labs rather than weight or BMI alone, since BMI cannot show fat versus muscle." Pay attention to your physical strength as well
While the FDA may permit drug compounding under certain circumstances, these versions of the medication are not approved or regulated by the FDA for safety and efficacy
Communication with your provider is crucial for reporting any concerning symptoms during your treatment