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Serum Lipid Peroxide (MDA) was estimated by k
Key highlights Tirzepatide (also known by FDA-approved brand names Mounjaro and Zepbound) is a dual receptor agonist (GLP-1/GIP) that helps reduce appetite, control blood sugar, and promote greater weight loss than single receptor GLP-1 receptor agonists, such as semaglutide
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Studies using hippocampal tissue obtained from patients with temporal lobe epilepsy and a mouse model of pilocarpine-induced epilepsy have shown that decreased GLP-1R expression in hippocampal microglia correlates with increased cytokine release and astrocyte activation [73]
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