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The flushing of the face is very temporary and usually occurs within 10 minutes of administering Melanotan II
The frequency of treatment failure may be significant in patients treated with MIL, which has supplanted antimonials in the kala-azar extermination campaign in nations such as India, even though it has been noted in patients treated with the majority of anti-leishmanials
Sulfur donors The main principle of this is to detoxify the excess CN-methemoglobinemia combined with thiosulfate (sulfur donors) to form thiocyanate
Some develop into firm nodules that sit beneath the skin for days
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