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Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial

The breadth of reported activity reflects the compound's broad gene-expression effects

Glutathione is an important antioxidant in the lungs, but its concentration is low in the airways of patients with cystic fibrosis, since GSH is transported into the airways by the cystic fibrosis transmembrane conductance regulator, which is mutated in cystic fibrosis patients (111)

28 Additionally, a 16-week trial of supplementation with GlyNAC (which boosts glutathione levels) in older adults improvedand in some cases reversedmultiple hallmarks of aging, including inflammation, mitochondrial dysfunction, and oxidative stress

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Finasteride reduces DHT (root cause)