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J Clin Invest 107(1):711
As molecular complexity increases, demand for peptide APIs, peptide synthesis, GMP manufacturing systems, purification technologies, and cold-chain infrastructure will continue to grow
Inhibition of the Xc- transport system and depletion of cystine The Xc- transport system, which is composed of SLC7A11 and SLC3A2 proteins imports cystine into the cell while exporting glutamate
Keep a medication log: Track your doses to ensure you're staying on schedule
This raises important questions about how we assess meaningful benefit while ensuring timely access and maintaining scientific robustness
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