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While efficacy endpoints for weight loss in those trials were modest, the compound exhibited a favorable safety profile, supporting its later GRAS designation for food use

Dysesthesia (altered skin sensation) as a GLP-1-class effect retatrutide TRIUMPH-1 treatment-emergent rate 5.1 / 12.3 / 12.5% at 4 / 9 / 12 mg vs 0.9% placebo

J Natl Cancer Inst

However, as with any medical intervention, its crucial for individuals to consult with their healthcare providers before initiating B12 supplementation

It's not always the case but it does come to mind

The vitamin plays a crucial role in maintaining neurological function and neurotransmitter regulation