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Unlike semaglutide (prescribed as Ozempic and Wegovy), which are in the class of drugs known as GLP-1 receptor agonists, tirzepatide is a dual GIP and GLP-1 receptor agonist, and a series of trials have already demonstrated that tirzepatide appears to be more effective than semaglutide
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Compounded semaglutide contains the same active ingredient but may include additional compounds that could slightly alter the GI experience
Understanding Growth Hormone Secretagogues Before comparing these two peptides directly, understanding the broader category of growth hormone secretagogues provides necessary context for individuals researching this area with their healthcare providers
In the management of type 2 diabetes, the American Diabetes Association and the European Association for the Study of Diabetes emphasize a holistic patient-centered approach that considers comorbidities like obesity, chronic kidney disease, hypertension and cardiovascular disease when selecting treatments (135)