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With age, mGSH declines selectively, contributing to the mitochondrial dysfunction that underpins the "mitochondrial theory of aging." Restoring systemic GSH levels supports mGSH replenishment, with downstream effects on cellular energy production and biological aging rate
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The mechanisms are now well established, and the consistency of preclinical outcomes is why Ive personally continued to use GHK-Cu for years
In this work, after treatment with GSH combined with CG, compared with the control group, the levels of serum TNF- and IL-17 in the treatment group significantly decreased
However, high doses can cause: Stomach upset or diarrhea Kidney stones in susceptible individuals Iron absorption issues if you have iron overload conditions People with kidney problems should be cautious with high-dose vitamin C supplements
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