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Additionally, since cardiovascular disease and diabetes are known risk factors for cognitive decline and dementia, there is hope with some preliminary evidence that these drugs may have a protective effect against neurodegenerative disorders

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*Note that nutritional percentages reported are only estimated values, and are indicated as such as (est)

Recruitment of participants was carried out between September 2021 and February 2023 in the general ICU

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Camellia sinensis ), quercetin ( Allium cepa, Malus domestica ), baicalin ( Scutellaria baicalensis ), and berberine ( Berberis spp .) have been reported to suppress S aggregation, improve mitochondrial function, and preserve dopaminergic neurons by modulating sirtuin and PI3K/Akt signaling pathways ( This article delineates the mechanistic interplay in PD between S pathology, sirtuin dysregulation, and impaired insulin signaling, illustrating how systemic metabolic dysfunction may contribute to the progression of neurodegeneration