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Abstract The liver is a highly specialized organ that plays a pivotal role in the detoxification of numerous substances

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Carnitine O -acetyltransferase Carnitine O -acetyltransferase (CrAT), located primarily in the mitochondrial matrix, catalyzes the addition or the removal of carnitine from medium- and short-chain acyl-CoA 60,61 , facilitating the efflux of mitochondrial acetyl-CoA to the cytosol and buffering the intracellular pools of acetyl-CoA and carnitine

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J Vet Med Sci 2007, 69(12):1263-1270

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