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Could I be deficient in Vitamin B12
Will I Need Downtime
User 3 split his 500mcg dose as 250mcg every 12 hours specifically to account for what he cited as a 4 to 6-hour half-life
This is the standard for medical and laboratory refrigeration, as its cold enough to suppress microbial growth without the risk of freezing
Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning
Mar 31, 2026 You just got your first vial of GLP-1 medication
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