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Ipamorelin, on the other hand, is studied for its selective action on GH secretion with minimal impact on other hormones
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To explore this idea, we bred the MMTV-PyMT transgenic mouse strain (which spontaneously develops breast tumours) 26 with an uninduced Gclc f/f Rosa26 creERT2 mouse 27 in which the rate-limiting step in GSH synthesis, the glutamatecysteine ligase catalytic subunit (GCLC), can be knocked out throughout the body after induction with tamoxifen
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This suppression of somatostatin levels by ipamorelin encourages the body to naturally increase its GH levels [1]
