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The study included non-diabetic patients with asthma across three BMI categories: Overweight (BMI 25.0029.99 kg/m) Obese (BMI 30.0040.00 kg/m) Morbidly obese (BMI 40.00 kg/m) Patients initiating a GLP-1 receptor agonist were compared with matched controls without GLP-1 exposure over a three-year follow-up period

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The mechanism involves both central nervous system pathways in the hypothalamus and peripheral pathways through melanocortin receptors in spinal cord and penile tissue

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These reactions typically include redness, swelling, and mild pain at the injection site