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Mechanistic differences: Matrixyl acts as a matrikine -- a peptide fragment derived from extracellular matrix proteins that signals cells to increase collagen synthesis
GCGR activation stimulates hepatic glucose production between meals, increases lipolysis and fatty acid oxidation in the liver, elevates basal energy expenditure, and promotes thermogenesis
This is significant because it establishes direct FDA contact with Peptide Sciences
doi:10.1016/j.bbcan.2014.04.004
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