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In clinical studies, medications that act on these receptors have been associated with weight reduction in certain patient populations when combined with lifestyle modification

If significant mood effects occur, discontinue use and consult a healthcare provider

However, STEP 1 extension concluded that 1-year withdrawal of semaglutide results in regain of two-thirds of prior weight loss [97], highlighting that withdrawal of semaglutide results in weight regain which may be problematic in older adults who are already using polypharmacy approaches for comorbid disease

Yubero-SerranoEMGonzalez-GuardiaLRangel-ZuigaODelgado-CasadoNDelgado-ListaJPerez-MartinezPet alPostprandial antioxidant gene expression is modified by Mediterranean diet supplemented with coenzyme Q10 in elderly men and women

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