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The mechanism of action has not changed, only the addition of a nausea-dampening cofactor that may make the critical early weeks and dose escalation phases manageable

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The American Society of Anesthesiologists warns that patients on Ozempic or the other semaglutide or liraglutide medicines should stop taking them a week before any surgery, since they can increase the risk of regurgitation during surgery even if the patient has been fasting

GLP-1 reduces glucagon levels, preventing unnecessary sugar release into the blood

F.DalgaS.UmudumZ.BakanN.et al (2002)

This shift enlarges the addressable market significantly