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The triple receptor activation produces even more aggressive appetite suppression, which correlates with more pronounced gastric emptying delays
Voyvodic PL, Min D, Liu R, Williams E, Chitalia V, Dunn AK, Baker AB
The study is Long-term weight loss effects of semaglutide in ob*sity without diabetes in the SELECT trial by Ryan et al, published in the Nature Medicine Journal
This demonstrates that GLP-1R function is critical for normal brain metabolic function
Beyond weight loss, a major NEJM trial also found that semaglutide significantly reduces the risk of major cardiovascular events in patients with obesity and established cardiovascular disease a finding we covered in our post on GLP-1 injections and heart health
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