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Screening catches contraindications, slow titration limits side effects, and regular check ins keep the plan on track and adjust it if the response stalls

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These are typically worst during initial dose titration and improve over 48 weeks

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In practical terms, preservation usually requires: Resistance training at least two times per week Protein intake between 1.2 and 1.6 grams per kilogram of body weight per day Without these inputs, weight loss may still occur, but a larger proportion of that loss may come from lean tissue rather than fat

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