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Endocrinology 133 , 12921299 (1993)
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References 1 EUMOFA
10.1023/a:1018893220943 113 SikiricP.PetekM.RucmanR.SeiwerthS.GrabarevicZ.RotkvicI.et al (1993)
But in general, turning a peptide (including GLP-1 or insulin) into an oral formulation means overcoming three major challenges: protecting the peptide from digestion in the stomach, improving absorption of the peptide via the gut, and slowing down the enzymatic breakdown and excretion of the peptide once it is in the blood
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