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Suboptimal thyroid activity slows metabolism and can create a ceiling effect on weight loss that has nothing to do with Retatrutide effectiveness
In a phase 2 clinical trial targeting obese individuals without type 2 diabetes (T2D), retatrutide dosed at 1 to 12 mg resulted in up to 24.2% weight loss over a 48-week treatment period, compared to 2.1% in the placebo group, and demonstrated a dose-dependent effect
Liraglutide in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials
J Int Soc Sports Nutr
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Res (2018) 16:26
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