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Desprs JP, Lemieux I

Flavored with lemon, cucumber, or electrolyte powder if plain water is difficult

N Engl J Med 375:311322 Holman RR, Bethel MA, Mentz RJ et al (2017) SUSTAIN-6 Investigators Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

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Discontinuation due to adverse events: TRIUMPH-2 placebo 4.9%, 4 mg 3.8%, 9 mg 11.6%, 12 mg 7.7% TRIUMPH-3 placebo 4.8%, 9 mg 9.8%, 12 mg 13.5% TRIUMPH-3s 13.5% is the highest figure we have for this molecule

Because its acetyl shield allows it to bypass the digestive tract and enter the cells intact, it provides an immediate infusion of active, reduced glutathione directly into the cytoplasm