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In a meta-analysis of major RCTs, GLP-1RAs reduced composite major CV events by 14% (hazard ratio [HR], 0.86
On average, patients who take weight loss injections can expect to lose 15% of their body weight
At higher doses, patients lost an average of nearly a quarter of their body weight, exceeding outcomes typically reported with current licensed treatments such as Wegovy (~15%) or Mounjaro (~20%)
PMID 26797586
The TRIUMPH-5 study will provide data for a direct comparison between tirzepatide and retatrutide for WL
Most patients notice subtle appetite changes within the first week, with measurable weight loss appearing after 412 weeks
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