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May Improve Tolerability During Early Treatment Research on gradual titration of semaglutide indicates that slower dose escalation may be associated with fewer gastrointestinal side effects, including nausea, vomiting, and diarrhea, and better treatment adherence compared with label-speed escalation

Its scenario table directs anyone who becomes pregnant while taking semaglutide to contact their provider immediately for an individual risk assessment and monitoring plan

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Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples

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