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This was reported in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo

Using a smaller volume syringe (e.g., 0.3mL or 0.5mL) can make it easier to accurately measure smaller doses, as the unit markings are spaced further apart

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The initial dosage for semaglutide microdosing is typically 0.05 mg for the first 4 weeks

Even though we confirmed that astrocyte activation induces lactate release in the extracellular space, we cannot exclude that other mechanisms might be activated by optogenetic stimulation of astrocytes