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NDA filing anticipated 20272028 (est.) : FDA review (~10 months)

Current status and baseline characteristics Both STEP-HFpEF and STEP-HFpEF DM trials are fully enrolled and currently in the follow-up phases

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These medications work by slowing down the digestive process, reducing appetite, and promoting a feeling of fullness

Some practitioners recommend even higher oral doses of 10 to 15 grams daily for patients specifically targeting collagen synthesis during rapid weight loss, addressing the estimated 10-gram daily glycine deficit for a 70-kilogram adult

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