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Diabetes 58 , 29392945 (2009)

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These symptoms may indicate pyelonephritis, sepsis, or severe dehydration requiring intravenous antibiotics and fluids

The published volume limits are: Abdomen: 1.5 mL maximum per site Thigh: 1.0 mL maximum per site Upper arm: 0.5 mL maximum per site These limits come from a 2014 pharmacokinetic study (Usach et al., Journal of Controlled Release ) that measured solution retention after subcutaneous injection at increasing volumes

Should any abnormal result be repeated under more standardized conditions

Week 3 : 5,000-7,000 steps per day, plus one or two 20-minute walking workouts at a medium to brisk pace