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Arginine deiminase is derived from micro-organisms and human cells do not produce such enzyme [130]

In contrast, the human microbiome varies dramatically by geography, age, sex, and diet [116, 117]

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10.1002/ptr.70083 62 NovakV.MantzorosC

So far, six c-Met inhibitors have entered clinical trials and have been shown to inhibit tumor growth and invasion

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