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We use the Charles River Endosafe PTS system to test for bacterial endotoxins following USP guidelines: The following are suitability parameters that verify the system was working properly and the sample prep dilution is appropriate for accurate results
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Schedule (Once Weekly Injection) Upper limit: 12 mg per week is the highest dose used in the major published clinical trials (Phase 2 obesity, Phase 2 type 2 diabetes, and the Phase 3 TRIUMPH-4 and TRANSCEND-T2D-1 studies)
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Vitamin B12 level
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