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10.1371/journal.pone.0006733 3 BrayJ
The utilisation of combination drug holds considerable promise, as they can circumvent the limitations inherent in single-agent drug
Moreover, it is crucial to modify the dosage, select the least toxic medication, and consider additional risk factors for SNHL (exposure to noise, age, concomitant ototoxic drugs, etc.) (Reynard and Thai-Van 2024)
In the STEP TEENS trial, once-weekly semaglutide resulted in approximately 16% mean body weight reduction over 68 weeks, while liraglutide produced more modest reductions
This is most common during the first 12 weeks when weight loss is fastest and typically resolves as weight loss decelerates
An open-label, single-center, case-control pilot study investigated the effects of GLP-1RAs in individuals with idiopathic intracranial hypertension (IIH) and obesity (BMI 30 kg/m) [98] (Fig
