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In total, more than 300 constituents have been identified in propolis samples, whereas the biological activity of propolis has been mainly attributed to a handful of substances, including flavonoids, terpenes, caffeic acid, ferulic acid, cumaric acid and esters
Notably, GSH binding motif is not conserved among the other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) justifying their abilities to use wide variety of thiols like cysteine, protein thiols, mercaptoethanol, and dithiothreitol in addition to GSH as reducing equivalent for the catalysis [8, 17, 18]
10.1097/TA.0b013e31802ee542 60 SchachtruppA.WautersJ.WilmerA
(A) Metabolic pathways significantly altered in non-PT cells from ABMR samples compared to healthy samples, with corresponding NES and adjusted P-values
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